The work stems from the international LITMUS program (Liver Investigation: Testing Marker Utility in Steatohepatitis), a consortium involving 53 academic and industrial partners, including FFULisboa. The aim was to validate biomarkers that reduce the need for liver biopsy and optimize patient follow-up.
The study published in The Lancet evaluated blood tests and ultrasound elastography in over 1,500 patients across 13 countries, identifying gamma-GT as an effective tool for initial screening in medical routine.
In turn, the study published in Nature Medicine analyzed advanced magnetic resonance imaging techniques and serum biomarkers in 357 participants recruited from 9 countries, demonstrating the high precision of imaging in detecting advanced fibrosis and cirrhosis.




